Low Noise 5V to 400–1000V Adjustable HV Supply (1–200µA) for Portable System

Hi,

We are designing a compact, battery-powered system that requires a regulated high-voltage DC output with the following specifications:

• Input: 5V

• Output: Adjustable 400V to 1000V

• Load current: 1µA to 200µA

• Very low ripple and noise

• High efficiency and small form factor

The supply will be used as a bias source for sensitive detectors (e.g., APD/PMT-type devices), so output stability and low noise are critical. The output must remain stable across the specified load range.

I am currently considering a closed-loop flyback topology with post-filtering, but I am open to alternative architectures.

Could you please recommend:

• Suitable controller ICs from your portfolio?

• Relevant reference designs or evaluation boards?

• Design techniques for minimizing ripple and noise at these voltage levels?

Any guidance or application notes would be greatly appreciated.

Thank you.