Inverting regulator

Hi all, I want to design a power stage that has a 48VDC input and 2 adjustable outputs - one 50-200VDC and the other minus 50-200VDC. While the first is a fairly standard solution, we are having a lot of discussions about the negative one.
In summary, based on your experience what would be the best way of designing power supply like this:
Vin= 48V
Vout = -50 to -200V
Pmax = 150W

Do you have any solutions to generate such negative voltages? Any IC/system/architecture idea we could use in our design? Any feedback would be greatly appreciated.

Thank you in advance!

If these are isolated converters, just relabel the outputs on the - converter and tadah! you are done. Are these outputs moving together are these like rail voltages?

Yes, they are. The aim is to drive capacitive load with one side connected to earth.